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Wilmot Research

Wilmot Cancer Institute / Research / Faculty & Staff
 

Research Faculty

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M. Jacob Adams, M.D., M.P.HM. Jacob Adams, M.D., M.P.H
Email M. JacobAdams

Research Interest: Pediatric, cardiovascular and cancer epidemiology
Brian Altman, Ph.D.Brian J. Altman, Ph.D.
Email BrianAltman

Biomedical Genetics
Altman Lab

Research Interest: Role of Circadian Rhythm in in gene regulation and cancer cell biology and metabolism.
Jeffrey Andolina, M.D., M.S.Jeffrey R. Andolina, M.D., M.S.
Email JeffreyAndolina

Pediatrics

Research Interest: The treatment and comprehensive care for children with leukemia and lymphoma, including acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and chronic myeloid leukemia (CML), as well as the care for children with other cancers and blood diseases.
Robert Bambara, Ph.D.Robert A. Bambara, Ph.D.
Email RobertBambara

Microbiology & Immunology

Research Interest: Human genome stability, DNA damage response, HIV replication and evolution
Paul Barr, M.D.Paul M. Barr, M.D.
Email PaulBarr

Medicine

Research Interest: The development of novel therapeutics for patients with chronic lymphocytic leukemia and lymphoma.
Michael Becker, M.D.Michael Becker, M.D.
Email MichaelBecker

Medicine

Research Interest: Malignant stem cell populations in myeloid neoplasms
Danielle Benoit, Ph.D.Danielle Benoit, Ph.D.
Email DanielleBenoit

Biomedical Engineering
Benoit Lab

Research Interest: Therapeutic biomaterials development for tissue engineering and drug delivery with applications ranging from bone regeneration to antioral biofilm treatments
Benoit Biteau, Ph.D.Benoit Biteau, Ph.D.
Email BenoitBiteau

Biomedical Genetics
Biteau Lab

Research Interest: Molecular and Cellular Mechanisms that Control Tissue Homeostasis and Somatic Stem Cells
Dirk Bohmann, Ph.D.Dirk Bohmann, Ph.D.
Email DirkBohmann

Biomedical Genetics
Bohmann Lab

Research Interest: The biochemistry, molecular biology and genetics of signal-transducing transcription factors and their role in development, aging and disease
Edward Brown, Ph.D.Edward Brown, Ph.D.
Email EdwardBrown

Biomedical Engineering
Brown Lab

Research Interest: Multiphoton Laser Scanning Microscopy, novel in vivo imaging and measurement techniques, tumor biology, angiogenesis
Marc Brown, M.D.Marc D. Brown, M.D.
Email MarcBrown

Dermatology

Research Interest: Mohs surgery, melanoma, facial reconstruction, and challenging and unusual skin cancers
W. Richard Burack, M.D., Ph.D.W. Richard Burack, M.D., Ph.D.
Email W. RichardBurack

Pathology & Laboratory Medicine
Burack Lab

Research Interest: Activation induced cytidine deaminase (AID) impact on Follicular lymphoma (FL) tumors as a prognostic factor for Diffuse Large B-cell lymphoma (DLBCL)
Laura Calvi, M.D.Laura M. Calvi, M.D.
Email LauraCalvi

Medicine
Calvi Lab

Research Interest: Cellular and Molecular Mechanisms of Microenvironmental Regulation of Hematopoietic Stem Cells in the Bone Marrow
Carla Casulo, M.D.Carla Casulo, M.D.
Email CarlaCasulo

Medicine

Research Interest: Newly diagnosed and relapsed Hodgkin lymphoma, mantle cell lymphoma, diffuse large B cell lymphoma ,and peripheral T cell lymphoma
Joe Chakkalakal, Ph.D.Joe V. Chakkalakal, Ph.D.
Email JoeChakkalakal

Pharmacology & Physiology
Chakkalakal Lab

Research Interest: Contribution of stem cells to the maturation, regeneration and lifelong maintenance of skeletal muscle in growth aging and cancer
Chawnshang Chang, Ph.D.Chawnshang Chang, Ph.D.
Email ChawnshangChang

Pathology & Laboratory Medicine
Chang Lab
George H. Whipple Laboratory for Cancer Research

Research Interest: Androgen receptor / Steroid hormones function and pathophysiology in the Prostate
Regine Choe, Ph.D.Regine Choe, Ph.D.
Email RegineChoe

Biomedical Engineering
Choe Lab

Research Interest: Diffuse optics for in vivo cancer detection, diagnosis and therapy monitoring
Charles Chu, Ph.D.Charles Chu, Ph.D.
Email CharlesChu

Medicine
Chu Lab

Research Interest: Translational Research in Lymphoid Malignancies
Andrew Evans, M.D., Ph.D.Andrew Evans, M.D., Ph.D.
Email AndrewEvans

Pathology & Laboratory Medicine
Calvi Lab

Research Interest: My current research focuses on the molecular, genetic, and immunologic mechanisms that underlie leukemia and lymphoma development. Specifically, I’m studying which bone marrow stromal interactions influence the development and persistence of these diseases. Other interests include the role of chronic viruses in lymphoma development, and the genetic characteristics that influence diagnosis and treatment of pre-myeloid leukemias or myelodysplastic syndromes.
Rudi Fasan, Ph.D.Rudi Fasan, Ph.D.
Email RudiFasan

Chemistry
Fasan Lab

Research Interest: Bioorganic chemistry, chemical biology, and biomolecular engineering and evolution
Jonathan Friedberg, M.D., M.M.Sc.Jonathan W. Friedberg, M.D., M.M.Sc.
Email JonathanFriedberg

Medicine

Research Interest: Development of novel therapies for patients with lymphoma
Benjamin Frisch, Ph.D.Benjamin Frisch, Ph.D.
Email BenjaminFrisch

Pathology & Laboratory Medicine

Research Interest: Role of inflammatory mediators in bone marrow microenvironmental dysfunction during hematologic malignancies
Chunkit Fung, M.D.Chunkit Fung, M.D.
Email ChunkitFung

Medicine

Research Interest: Cancer control, particularly in the development, implementation, and dissemination of mHealth behavioral interventions to prevent and manage treatment- and cancer-related toxicities in cancer survivors, with a specific focus in cardiovascular complications from cancer treatment
Ahmed Ghazi, M.D., M.Sc. Ahmed Ghazi, M.D., M.Sc.
Email AhmedGhazi

Urology
Simulation Innovation Lab

Research Interest: Surgical Simulation and Patient-Specific Surgical Simulation to create translational models to measure improvements in surgical training and patient outcomes.
Vera Gorbunova, Ph.D.Vera Gorbunova, Ph.D.
Email VeraGorbunova

Biology
Gorbunova & Seluanov Laboratory

Research Interest: Mechanisms of aging and the role of DNA repair and genomic instability in the aging process.
Stephen Hammes, M.D., Ph.D.Stephen R. Hammes, M.D., Ph.D.
Email StephenHammes

Medicine
Hammes Lab

Research Interest: Androgen Effects on Reproduction and Cancer
Aram Hezel, M.D.Aram Francis Hezel, M.D.
Email AramHezel

Medicine

Research Interest: The molecular biology and genetics of pancreatic and biliary tract cancers
David Hicks, M.D.David G. Hicks, M.D.
Email DavidHicks

Pathology & Laboratory Medicine

Research Interest: Metabolic and neoplastic bone disorders; breast pathology, with particular focus on prognostic molecular markers and development of advanced tissue-based diagnostic techniques
Wei Hsu, PhDWei Hsu, PhD
Email WeiHsu

Biomedical Genetics
Hsu Lab

Research Interest: Cellular Signaling in Neural Development and Disease
Michelle Janelsins-Benton, Ph.D.Michelle C. Janelsins-Benton, Ph.D.
Email MichelleJanelsins-Benton

Research Interest: Understanding clinical, psychological, and biological mechanisms of cognitive difficulties in cancer patients
Jean Joseph, M.D.Jean V. Joseph, M.D.
Email JeanJoseph

Urology

Research Interest: Laparoscopic/minimally invasive urology (prostatectomy, nephrectomy), reconstructive urology, hematuria, genitourinary cancers, kidney stones, benign prostatic hypertrophy (BPH), urethral strictures, vasectomy, vasectomy reversal
Charles Kamen, Ph.D.Charles S. Kamen, Ph.D.
Email CharlesKamen

Surgery

Research Interest: Factors that lead to health disparities among sexual and gender minority populations, specifically disparities in cancer-related health outcomes and psychological distress
Sarah Kerns, Ph.D., M.P.H.Sarah L. Kerns, Ph.D., M.P.H.
Email SarahKerns

Radiation Oncology

Research Interest: Radiogenomics - the study of genetic factors that are associated with increased risk of developing late effects from radiotherapy used in treatment of cancer
Clara Kielkopf, Ph.D.Clara L. Kielkopf, Ph.D.
Email ClaraKielkopf

Biochemistry & Biophysics
Kielkopf Lab

Research Interest: Splicing defects in hematologic malignancies; roles of human pre-mRNA splicing factors in HIV-1 infectivity; development of engineered splicing factors for correction of splicing defects; splice sites and their associated proteins as therapeutic targets.
Hartmut Land, Ph.D.Hartmut Land, Ph.D.
Email HartmutLand

Biomedical Genetics
Land Lab

Research Interest: Molecular mechanisms of carcinogenesis. Signaling and Cancer Cell Metabolism
Soo Ok Lee, Ph.D.Soo Ok Lee, Ph.D.
Email Soo OkLee

Pathology & Laboratory Medicine
Soo Ok Lee Lab

Research Interest: Signal Transduction Effects on Androgen Receptor
Yi-Fen Lee, Ph.D.Yi-Fen Lee, Ph.D.
Email Yi-FenLee

Urology
Yi-Fen Lee Lab

Research Interest: Extracellular vesicles (Evs), Exosomes, for their roles in cancer development, progression and response to treatment in Urology cancers.
Jane Liesveld, M.D.Jane Larae Liesveld, M.D.
Email JaneLiesveld

Medicine

Research Interest: Effects of oxygen metabolites/chemokines on hematopoietic stem cell expansion and preservation
Lynne Maquat, Ph.D.Lynne Maquat, Ph.D.
Email LynneMaquat

Biochemistry & Biophysics
Maquat Lab

Research Interest: RNA metabolism in human cells (nonsense-mediated mRNA decay/mRNA surveillance); influence of pre-mRNA splicing on mRNA translation; Staufen-mediated mRNA decay and Staufen-regulated RNA metabolism; post-transcriptional gene control via lncRNAs and SINEs; miRNA metabolism; Fragile X Mental Retardation Syndrome/Autism; therapeutics of nonsense diseases.
Scott McIntosh, Ph.D.Scott McIntosh, Ph.D.
Email ScottMcIntosh

Public Health Sciences

Research Interest: Smoking Cessation in special populations, Technology/Web Assisted Risk Behavior Intervention and Dissemination of effective interventions to physician practices
Stephano Mello, Ph.D.Stephano Mello, Ph.D.
Email StephanoMello

Biomedical Genetics
Mello Lab

Research Interest: Understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation.
Michael Milano, M.D., Ph.D.Michael Milano, M.D., Ph.D.
Email MichaelMilano

Radiation Oncology

Research Interest: Lung cancer and other thoracic tumors, head and neck cancer and metastatic cancer
Nimish Mohile, M.D.Nimish Mohile, M.D.
Email NimishMohile

Neurology

Research Interest: Understanding the role of cancer stem cells in the progression of brain tumors
Richard Moore, M.D.Richard G. Moore, M.D.
Email RichardMoore

Obstetrics & Gynecology

Research Interest: Ovarian cancer biomarker research for the early detection and management of ovarian cancer
Craig Mullen, M.D., Ph.D.Craig Mullen, M.D., Ph.D.
Email CraigMullen

Pediatrics

Research Interest: Cancer Immunobiology and Transplant Immunology
Joshua Munger, Ph.D.Joshua C. Munger, Ph.D.
Email JoshuaMunger

Biochemistry & Biophysics
Munger Lab

Research Interest: Mechanisms of metabolic network manipulation induced by viral infection and oncogenic mutation.
Patrick Murphy, Ph.D.Patrick J. Murphy, Ph.D.
Email PatrickMurphy

Biomedical Genetics
Murphy Lab

Research Interest: The genetics, genomics, and chromatin biochemistry of cell state transitions that occur during embryonic development and carcinogenesis.
Mark Noble, Ph.D.Mark Noble, Ph.D.
Email MarkNoble

Biomedical Genetics
Noble Lab

Research Interest: Neuro stem cell biology and medicine, developing pharmacological and cell based approaches to peripheral and spinal cord injury.
Jeanne O'Brien, M.D.Jeanne H. Sullivan O'Brien, M.D.
Email JeanneO'Brien

Urology

Research Interest: Male infertility, microsurgery, varicoceles and general Urology
Deborah Ossip, Ph.DDeborah J. Ossip, Ph.D
Email DeborahOssip

Public Health Sciences

Research Interest: Behavioral medicine and outcomes management include tobacco use and smoking interventions, obesity prevention and exercise
Catherine Ovitt, Ph.D.Catherine E. Ovitt, Ph.D.
Email CatherineOvitt

Biomedical Genetics
Ovitt Lab

Research Interest: Protective and regenerative strategies for salivary gland function and radiation therapies.
James Palis, M.D.James Palis, M.D.
Email JamesPalis

Pediatrics
Palis Lab

Research Interest: Cellular and Molecular events underlying the ontogeny of the hematopoietic system.
Luke Peppone, Ph.D.Luke Peppone, Ph.D.
Email LukePeppone

Surgery
Orthopaedics

Research Interest: The use of nutritional supplementation and exercise to treat the symptoms and side effects of cancer and its related treatment
Archibald Perkins, M.D., Ph.D.Archibald S. Perkins, M.D., Ph.D.
Email ArchibaldPerkins

Pathology & Laboratory Medicine
Perkins / Zhang Lab

Research Interest: Genetic mechanisms in acute myeloid leukemia and myelodysplastic syndrome with focus on the zinc finger oncoprotein EVI1
Edward Schwarz, Ph.D.Edward M. Schwarz, Ph.D.
Email EdwardSchwarz

Orthopaedics
Schwarz Lab

Research Interest: Inflammatory bone loss as seen in rheumatoid arthritis, infections, tumor metastasis and wear debris induced osteolysis around prosthetic implants
Glynis Scott, M.D.Glynis A. Scott, M.D.
Email GlynisScott

Dermatology
Scott Lab

Research Interest: Investigation into signaling pathways of prostaglandins in human melanocytes and melanoma and the role of Plexin receptors in melanocyte and melanoma biology.
Paula Vertino, Ph.D.Paula M. Vertino, Ph.D.
Email PaulaVertino

Biomedical Genetics

Research Interest: Cancer epigenetics: the role of DNA methylation and chromatin in driving cancer phenotypes and as a target for therapeutic intervention
Kevin Walter, M.D.Kevin A. Walter, M.D.
Email KevinWalter

Neurosurgery
Walter Lab

Research Interest: Brain Tumor Angiogenesis
Jacqueline Williams, Ph.D.Jacqueline Patricia Williams, Ph.D.
Email JacquelineWilliams

Environmental Medicine
Jacqueline Williams Lab

Research Interest: Discovering the effects of high (therapeutic) and low (environmentally-relevant) doses of radiation and their interactions with other toxic elements, such as commonly encountered infections, and better understanding differential effects of radiation in adults versus children.
Julie Wolf, Ph.D., M.P.H.Julie Wolf, Ph.D., M.P.H.
Email JulieWolf

Dermatology
Wolf Lab

Research Interest: Uncovering the biological mechanisms of radiation-induced skin toxicities
Guan Wu, M.D., Ph.D.Guan Wu, M.D., Ph.D.
Email GuanWu

Urology
Pathology & Laboratory Medicine

Research Interest: Genetic defects in kidney cancer cells and how these defects cause the disease
Shu-Yuan Yeh, Ph.D.Shu-Yuan Yeh, Ph.D.
Email Shu-YuanYeh

Urology
Yeh Lab
George H. Whipple Laboratory for Cancer Research

Research Interest: Role of the estrogen receptor (ER) and androgen receptor (AR) in urological diseases, including prostate cancer, bladder cancer, benign prostatic hyperplasia (BPH) and male fertility.
Clive Zent, M.D.Clive S. Zent, M.D.
Email CliveZent

Medicine
Zent Lab

Research Interest: Lymphoid Malignancy Research
Jiyong Zhao, Ph.D.Jiyong Zhao, Ph.D.
Email JiyongZhao

Biomedical Genetics
Land Lab
Zhao Lab

Research Interest: Signal transduction and development of therapeutic agents in B-lymphomas; Cell cycle regulation