Faculty K-P Kiernan, Amy , Ph.D. Boston College 1997 (Assistant Professor of Ophthalmology, Central for Aging and Developmental Biology) Molecular genetics of sensory disorders; investigating the development, differentiation, and survival of precursor cells in the eye and the inner ear. Krolewski, John J., M.D., Ph.D. New York University, 1984 (Professor and Chair, Pathology and Laboratory Medicine) Cytokine signaling: Pro-apoptotic therapeutics for prostate cancer; next-gen sequencing as a diagnostic for cancer. Lee, Yi-Fen , Ph.D. Wisconsin Madison, 1997 (Associate Professor of Urology and of Pathology and Laboratory Medicine) Non-genomic action of androgens and antiandrogens; vitamin D signaling in the prostate; physiological roles of the human testicular receptor 4. Li, Faqian , M.D. Hubei Medical University 1983, Ph.D. South Dakota 1996 (Associate Professor of Pathology and Laboratory Medicine) The molecular mechanisms that regulate cardiac myocyte shape and remodeling during heart hypertrophy and failure. Libby, Richard , Ph.D. Boston College 1997 (Assistant Professor of Ophthalmology) Neurobiology of glaucoma; mouse models and advanced mouse genetics to probe the pathophysiology of glaucoma; investigation of the molecular processes that lead to retinal ganglion cell (RGC) death in glaucoma and why RGCs are more likely to die in some patients than in others. Luebke, Anne, Ph.D. Johns Hopkins 1991 (Associate Professor of Biomedical Engineering ) Role of cochlear outer hair cells in hearing and hearing loss, at both the molecular and systems levels. Mayer-Proschel, Margot, Ph.D. Wuerzburg, Germany 1990 (Associate Professor of Biomedical Genetics) Biological and molecular mechanisms governing precursor cell division, differentiation and survival in the brain. Messing, Edward , M.D. NYU 1972 (Professor and Chair of Urology) Early detection, prevention and treatment of urologic malignancies. Miano, Joseph , Ph.D. New York Medical College 1992 (Associate Professor of Medicine, Aab Cardiovascular Research Institute) Smooth muscle cell differentiation control with special emphasis on transgenic mouse models, genomics, and bioinformatics. Milner, Laurie A. , M.D. Texas Southwestern, Dallas 1986 (Associate Professor of Pathology and Laboratory Medicine) Molecular mechanisms responsible for generation of diverse cell types from pluripotent stem cells; relation of aberrations in normal developmental pathways to pediatric malignancies. Mooney, Robert , Ph.D. Johns Hopkins 1980 (Professor of Pathology and Laboratory Medicine) Mechanisms of obesity-dependent insulin resistance in type 2 diabetes. Morrell, Craig N. , D.V.M. Tufts 2000, Ph.D. Johns Hopkins 2005 (Associate Professor of Medicine, Aab Cardiovascular Research Institute) Hemostastis/thrombosis and immune regulatory function of platelets, in vitro and in vivo. Nastiuk, Kent, Ph.D. Rockefeller University 1992 (Research Associate Professor, Pathology and Laboratory Medicine) Regulation of cell growth and apoptosis of normal prostate, benign prostatic hyperplasia (BPH), and prostate cancer by androgens and growth factors. Development of novel imaging modalities for mouse models of cancer. Noble, Mark D. , Ph.D. Stanford 1977 (Professor of Biomedical Genetics) Stem cell biology; regeneration in the central nervous system; redox modulation of precursor cell function; developmental disorders; brain tumor biology and adverse effects of chemotherapy on neural stem cell populations. O'Keefe, Regis J. , M.D., Ph.D. Harvard 1985, Ph.D. Rochester 2000 (Professor and Chair of Orthopaedics) Growth plate chondrocyte differentiation and maturation; biochemical mechanisms of prosthetic implant loosening; mechanisms of tumor mediated bone loss. Olshowka, John, Ph.D., University of California, Davis 1978 (Associate Professor of Neurobiology and Anatomy) There is increasing recognition of the importance for glia in all aspects of brain function ranging from normal homeostasis to repair and repopulation following injury. Our laboratories utilize mouse models to focus on the role of neuroinflammation in neurodegeneration and CNS injury. Ovitt, Catherine E. , Ph.D. Washington 1987 (Assistant Professor of Biomedical Genetics, Center for Oral Biology) Salivary gland function, maintenance, and repair. Palis, James , M.D. Rochester 1981 (Professor of Pediatrics in Hematology/Oncology, Professor of Oncology and Biomedical Genetics) Development of the hematopoietic system in the mammalian embryo. Perkins, Archibald S. , M.D., Ph.D. Columbia University 1986, 1987 (Professor of Pathology and Laboratory Medicine) Genetic mechanisms of leukemogenesis. Phipps, Richard P. , Ph.D. Medical College of Virginia 1980 (Professor of Environmental Medicine) Genetic mechanisms of leukemogenes; lipid mediators as B lymphocyte adjuvants for vaccines; lung scarring and chronic obstructive pulmonary disease; platelet activation and regulation; and ocular inflammation and tissue remodeling. Proschel, Christoph , Ph.D. University of London (Assistant Professor of Biomedical Genetics) Astrocyte development and white matter disease. Puzas, J. Edward , Ph.D. Rochester 1976 (Donald and Mary Clark Professor of Orthopaedics) Molecular and cellular biology of the skeletal system.